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The St. Louis Post-Dispatch is the major city-wide newspaper in St. Louis, Missouri. Although written to serve Greater St. Louis, the Post-Dispatch is one of the largest newspapers in the midwestern United States, and is available and read as far west as Kansas City, Missouri, as far south as Memphis, Tennessee, and as far north as Springfield, Illinois. It is the one and only remaining printed daily newspaper in St. Louis.

As of 2011, the owner is Lee Enterprises of Davenport, Iowa, which purchased Pulitzer, Inc. in 2005 in a cash deal valued at $1.46 billion.
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